beta Arrestin 1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1750
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beta Arrestin
1 Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M, R
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50.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:2,000
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1:10-1:50
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1:50-1:200
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1:50-1:100
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1:50-1:200
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1:50-1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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beta Arrestin
1 Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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408(Human);
109689(Mouse); 25387(Rat)
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SwissProt
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P49407(Human);
Q8BWG8(Mouse); P29066(Rat)
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Synonyms
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Beta-arrestin-1;
Arrestin beta-1; ARRB1; ARR1
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Category
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GPCR & G
Protein
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Background
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The members of
the G protein coupled receptor family are distinguished by their slow
transmitting response to ligand binding. These seven transmembrane proteins
include the adrenergic, serotonin and dopamine receptors. The effect of the
signaling molecule can be excitatory or inhibitory depending on the type of
receptor to which it binds. Members of theβ-Arrestin family
regulate receptor binding to G proteins. β-Arrestins
have been found to be located at postsynaptic sites, where they are thought
to act in concert withβARK (βARK1,
also designated GRK 2, orβARK2, also designated GRK 3
to regulate G protein-coupled neurotransmitter receptors. Expression ofβ-Arrestin-1 and b-Arrestin-2 is seen predominantly in spleen and
neuronal tissues. It has been shown thatβ-Arrestin-1
expression is modulated by intracellular cAMP, which may be a novel mechanism
for the regulation of receptor-mediated responses.
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包装清单:
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产品编号
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产品名称
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包装
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XY1750
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beta Arrestin
1 Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
beta Arrestin 1
Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10