YAP1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1615
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YAP1 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H
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65.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液,可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整):
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:2,000
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1:10-1:50
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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YAP1 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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10413(Human)
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SwissProt
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P46937(Human)
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Synonyms
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COB1; YAP;
YAP2; YAP65; YKI
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Category
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Protein
Tyrosine Kinase; Cancer Biology
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Background
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Commitment to
cell division occurs at a point late in the G1 phase of the cell cycle,
termed Start. Passage through Start requires the activation of the Cdc28
protein kinase by the cell cycle-regulated G1 cyclins. Maximal expression of
these G1 cyclins is induced by the heterodimeric transcription factor complex
composed of Swi4 (also designated Art1) and Swi6. Swi4 is the DNA-binding
subunit of this complex. In addition to binding Swi4, Swi6 forms a complex
with Mbp1. This complex activates S-phase cyclins and genes involved in DNA
synthesis Rpb1 is the largest subunit of the yeast RNA polymerase II. Srb4 is
a basal transcription factor that is essential for the establishment of the
transcription initiation apparatus. Stress factors induce transcription through
the induction of various transcription factors. Yap1 activates expression in
response to oxidative stress, while Msn2 and Msn4 mediate transcription via
the stress response element (STRE).
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包装清单:
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产品编号
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产品名称
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包装
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XY1615
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YAP1 Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
YAP1 Rabbit
Monoclonal Antibody -20℃保存,Western一抗稀释液-20℃或4℃保存,一年有效。Western一抗稀释液优先推荐4℃保存,长期不使用可以考虑-20℃保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验,请注意回收使用过的稀释抗体?;厥盏目固逋ǔV辽倏梢灾馗词褂?span>5-10