LGR5/GPR49 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1582
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LGR5/GPR49
Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, FC
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H, M, R
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100.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000
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1:10-1:50
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-
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-
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-
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1:50-1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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LGR5/GPR49
Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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8549(Human);
14160(Mouse); 299802(Rat)
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SwissProt
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O75473(Human);
Q9Z1P4(Mouse); D4AC13(Rat)
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Synonyms
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FEX; GPR49;
GPR67; GRP49; HG38
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Category
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GPCR & G
Protein
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Background
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G
protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM)
receptors or heptahelical receptors, interact with G proteins (heterotrimeric
GTPases) to synthesize intracellular second messengers, such as
diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their
diverse biological functions range from vision and olfaction to neuronal and
endocrine signaling and are involved in many pathological conditions. LGR5
(leucine-rich repeat-containing G-protein coupled receptor 5), also known as
GPR49 or GPR67, is a 907 amino acid multi-pass membrane protein that contains
17 leucine-rich repeats and belongs to the G protein-coupled receptor family.
Expressed in placenta, skeletal muscle and spinal cord, LGR5 functions as an
orphan receptor that is thought to play an important role in embryonic growth
control and cellular differentiation. Overexpression of LGR5 is associated
with increased tumor susceptibility and malignant transformation, implicating
LGR5 as a potent tumor-inducing protein.
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包装清单:
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产品编号
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产品名称
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包装
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XY1582
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LGR5/GPR49
Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
LGR5/GPR49
Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10