Plectin Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1561
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Plectin Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IHC
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H, M, R
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531.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000
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1:10-1:50
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-
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1:100-1:500
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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Plectin Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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5339(Human);
18810(Mouse); 64204(Rat)
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SwissProt
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Q15149(Human);
Q9QXS1(Mouse); P30427(Rat)
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Synonyms
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PCN; PLTN;
Hemidesmosomal protein 1; HD1; Plectin-1; PLEC; PLEC1
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Category
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Cytoskeletal
Signaling
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Background
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Plectin is an
abundant cytoskeletal protein that is involved in cytoplasm stabilization.
Plectin has been shown to crosslink intermediate filaments to microtubules
and microfilaments, and to anchor intermediate filaments to the plasma and
nuclear membranes. Plectin binds both Lamin B and vimentin, and this binding
is regulated by a variety of protein kinases. Phosphorylation by PKA or PKC
results in decreased binding to Lamin B, and phosphorylation by PKA enhances
the plectin-vimentin interactions. Plectin is also a substrate for p34cdc2
kinase. Several alternative splice isoforms of plectin are known to exist.
Mutations in human plectin are known to cause epidermolysis bullosa simplex
with muscular dystrophy (EBS-MD).
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包装清单:
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产品编号
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产品名称
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包装
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XY1561
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Plectin Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
Plectin Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10