PI 3 Kinase Class 3 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1549
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PI 3 Kinase
Class 3 Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IHC
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H, M, R
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100.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000
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-
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-
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1:50-1:200
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-
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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PI 3 Kinase
Class 3 Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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5289(Human);
225326(Mouse); 65052(Rat)
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SwissProt
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Q8NEB9(Human);
Q6PF93(Mouse); O88763(Rat)
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Synonyms
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Phosphatidylinositol
3-kinase catalytic subunit type 3; PI3-kinase type 3; PI3K type 3;
PtdIns-3-kinase type 3; Phosphatidylinositol 3-kinase p100 subunit; hVps34;
PIK3C3; VPS34
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Category
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Immunology/Inflamation;
Metabolism
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Background
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Phosphatidylinositol
3-kinases (PI3Ks) phosphorylate the 3' OH position of the inositol ring of
inositol lipids. PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit),
also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase, class III), is a
member of the PI3/PI4-kinase family. It is ubiquitously expressed with
predominant expression in skeletal muscle and is believed to participate in
endosome to lysosome transport, multivesicular body formation, autophagy and
retrograde endosome to Golgi transport. PI 3-kinase p100 is the catalytic
subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory
subunit of class 3 PI3Ks. PI 3-kinase p100 exclusively phosphorylates
phosphatidylinositol to produce PtdIns3P. Unlike class I PI3Ks, whose activities
are enhanced in the presence of magnesium, PI 3-kinase p100 activity is
enhanced by manganese. Its activity can also be regulated by nutrients,
suggesting an important role of PI-3 kinase p100 in the regulation of mTOR
protein synthesis and autophagy.
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包装清单:
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产品编号
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产品名称
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包装
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XY1549
|
PI 3 Kinase
Class 3 Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
PI 3 Kinase
Class 3 Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10