STAT6 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1534
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STAT6 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IF, IP,
IHC, ICC
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H, M
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94.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:2,000
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-
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1:50-1:200
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1:50-1:200
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1:50-1:200
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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STAT6 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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6778(Human);
20852(Mouse)
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SwissProt
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P42226(Human);
P52633(Mouse)
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Synonyms
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D12S1644;
IL-4-STAT; STAT6B; STAT6C
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Category
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Immunology/Inflamation
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Background
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Membrane
receptor signaling by various ligands, including interferons and growth
hormones such as EGF, induces activation of JAK kinases which then leads to
tyrosine phosphorylation of proteins that have been designated Stats (signal
transducers and activators of transcription). The first members of this
family to be described include Stat1α p91, Stat1β p84 (a form of p91 that lacks 38 COOH-terminal amino acids) and
Stat2 p113. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which
is part of the ISGF3 transcription factor complex. Stat3, which becomes
activated in response to epidermal growth factor (EGF) and interleukin-6
(IL-6), but not interferon-© (IFN-©) or Stat4, is an additional member of
this family. It has been suggested that the phosphorylated forms of both
Stat3 and Stat4 form homodimers as well as heterodimers with the other
members of the Stat family, and that differential activation of different
Stat proteins in response to different ligands should help to explain
specificity in nuclear signaling from the cell surface. Highest expression of
Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an
activator of Stat4. Other members of the Stat family include Stat5, which has
been shown to be activated by prolactin and by IL-3, and Stat6 (also
designated IL-4 Stat), which is involved in IL-4-activated signaling
pathways.
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包装清单:
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产品编号
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产品名称
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包装
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XY1534
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STAT6 Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
STAT6 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10