DNAJC15 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1519
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DNAJC15 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IHC
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H, M, R
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16.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:5,000
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-
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-
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1:50-1:200
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-
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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DNAJC15 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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29103(Human);
66148(Mouse); 290370(Rat)
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SwissProt
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Q9Y5T4(Human);
Q78YY6(Mouse)
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Synonyms
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Dnajd1; DnaJ
homolog subfamily C member 15; Cell growth-inhibiting gene 22 protein;
Methylation-controlled J protein; MCJ; DNAJD1; GIG22; HSD18
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Category
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Cancer Biology
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Background
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The DnaJ
family is one of the largest of all the chaperone families and has evolved
with diverse cellular localization and functions. The presence of a J domain
defines a protein as a member of the DnaJ family. DnaJ heat shock induced
proteins are from the bacterium Escherichia coli and are under the control of
the htpR regulatory protein. The DnaJ proteins play a critical role in the
HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP
hydrolysis. DnaJ proteins are important mediators of proteolysis and are
involved in the regulation of protein degradation, exocytosis and
endocytosis. MCJ (methylation-controlled J protein), also known as HSD18,
DNAJD1 or DNAJC15, is a 150 amino acid ubiquitously expressed single-pass
membrane protein containing one J domain. Localizing to the golgi apparatus
and only present in vertebrates, MCJ may be associated with increased
chemotherapeutic resistance in ovarian cancer by inducing expression of the
Mdr drug transporter and preventing intracellular drug accumulation.
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包装清单:
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产品编号
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产品名称
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包装
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XY1519
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DNAJC15 Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
DNAJC15 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10