PTEN Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1426
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PTEN Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IF, IHC,
ICC
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H, M, R
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54.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:5,000
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-
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1:50-1:500
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1:50-1:200
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1:50-1:500
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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PTEN Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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5728(Human);
19211(Mouse); 50557(Rat)
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SwissProt
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P60484(Human);
O08586(Mouse); O54857(Rat)
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Synonyms
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10q23del; BZS;
CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1
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Category
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PI3K/Akt/mTOR
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Background
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As human
tumors progress to advanced stages, one genetic alteration that occurs at
high frequency is a loss of heterozygosity (LOH) at chromosome 10q23. Mapping
of homozygous deletions on this chromosome led to the isolation of the PTEN
gene, also designated MMAC1 (for mutated in multiple advanced cancers) and
TEP1. This candidate tumor suppressor gene exhibits a high frequency of
mutations in human glioblastomas and is also mutated in other cancers,
including sporadic brain, breast, kidney and prostate cancers. PTEN has been
associated with Cowden disease, an autosomal dominant cancer predisposition
syndrome. The PTEN gene product is a putative protein tyrosine phosphatase
that is localized to the cytoplasm and shares extensive homology with the
cytoskeletal proteins tensin and auxilin. Gene transfer studies have
indicated that the phosphatase domain of PTEN is essential for growth
suppression of glioma cells.
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包装清单:
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产品编号
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产品名称
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包装
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XY1426
|
PTEN Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
PTEN Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10