FAK Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1108
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FAK Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M, R
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119.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1000-1:2000
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:200
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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FAK Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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5747(Human);
14083(Mouse); 25614(Rat)
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SwissProt
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Q05397(Human);
P34152(Mouse); O35346(Rat)
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Synonyms
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FAK; FADK;
FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
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Category
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Apoptosis
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Background
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Focal adhesion
kinase was initially identified as a major substrate for the intrinsic
protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid
sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase
whose sequence and structural organization are unique as compared to other
proteins described to date. Localization of p125 by immunofluorescence
suggests that it is primarily found in cellular focal adhesions leading to
its designation as focal adhesion kinase (FAK). FAK is concentrated at the
basal edge of only those basal keratinocytes that are actively migrating and
rapidly proliferating in repairing burn wounds and is activated and localized
to the focal adhesions of spreading keratinocytes in culture. Thus, it has been
postulated that FAK may have an important in vivo role in the
reepithelialization of human wounds. FAK protein tyrosine kinase activity has
also been shown to increase in cells stimulated to grow by use of mitogenic
neuropeptides or neurotransmitters acting through G protein coupled
receptors.
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包装清单:
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产品编号
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产品名称
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包装
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XY1108
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FAK Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
FAK Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10