SHP1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1093
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SHP1 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M, R
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68.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:500-1:1000
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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SHP1 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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5777(Human);
15170(Mouse); 116689(Rat)
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SwissProt
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P29350(Human);
P29351(Mouse); P81718(Rat)
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Synonyms
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HCP; HCPH;
SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
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Category
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Immunology/Inflamation
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Background
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The steady
state of protein tyrosyl phosphorylation in cells is regulated by the
opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs).
Several groups have independently identified a non-transmembrane PTP,
designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily
expressed in hematopoietic cells and characterized by the presence of two SH2
domains N-terminal to the PTP domain. SH2 domains generally mediate the
association of regulatory molecules with specific phosphotyrosine-containing
sites on autophosphorylated receptors, thereby controlling the initial
interaction of receptors with these substrates. A second and much more widely
expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has
been identified. Strong sequence similarity between SH-PTP2 and the
Drosophila gene corkscrew (CSW) and their similar patterns of expression
suggest that SH-PTP2 is the human corkscrew homolog.
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包装清单:
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产品编号
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产品名称
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包装
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XY1093
|
SHP1 Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
SHP1 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10