Glucose Transporter GLUT1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1015
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Glucose
Transporter GLUT1 Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M, R
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54.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:500-1:1000
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:10-1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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Glucose
Transporter GLUT1 Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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6513(Human);
20525(Mouse); 24778(Rat)
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SwissProt
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P11166(Human);
P17809(Mouse); P11167(Rat)
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Synonyms
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CSE; PED;
DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; SDCHCN; GLUT1DS
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Category
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Metabolism
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Background
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Glucose is
fundamental to the metabolism of mammalian cells. Its passage across cell
membranes is mediated by a family of transporters termed glucose transporters
or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and
dramatic increase in glucose uptake, which is largely due to the
redistribution of the insulin-inducible glucose transporter, Glut4. In
response to insulin, Glut4 is quickly shuttled from an intracellular storage
site to the plasma membrane, where it binds glucose. In contrast, the
ubiquitously expressed glucose transporter Glut1 is constitutively targeted
to the plasma membrane, and shows a much less dramatic translocation in
response to insulin. Glut1 and Glut4 are twelve-pass transmembrane proteins
(12TM) whose carboxy-termini may dictate their cellular localization.
Aberrant Glut4 expression has been suggested to contribute to such maladies
as obesity and diabetes. Glut4 null mice have shown that while functional
Glut4 protein is not required for maintaining normal glucose levels, it is
necessary for sustained growth, normal cellular glucose, fat metabolism and
prolonged longevity.
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包装清单:
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产品编号
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产品名称
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包装
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XY1015
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Glucose
Transporter GLUT1 Rabbit Monoclonal Antibody
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50μl
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AZ050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
Glucose
Transporter GLUT1 Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10