MAPK14 Mouse Monoclonal Antibody
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY0222
|
MAPK14 Mouse
Monoclonal Antibody
|
50μl
|
416.00元
|
|
来源
|
用途
|
交叉反应性
|
分子量
|
|
Mouse
|
WB, ICC, IHC,
IF
|
H, M
|
40KDa
|
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
|
WB
|
IP
|
IF
|
IHC
|
ICC
|
FC
|
ELISA
|
ChIP
|
|
1:1000
|
-
|
1:20-1:40
|
1:20-1:40
|
1:20-1:40
|
-
|
-
|
-
|
抗体详细信息如下:
|
About this
Antibody
|
|
Name
|
MAPK14 Mouse
Monoclonal Antibody
|
|
Category
|
Monoclonal
antibody(mAb); Primary antibody
|
|
Isotype
|
IgG2a
|
|
Purification
|
ProA XYfinity
purified
|
|
About the
Immunogen
|
|
Immunogen
|
This antibody
is produced by immunizing mice with a synthetic peptide (KLH-coupled)
corresponding to a region of MAPK14.
|
|
Gene ID
|
1432
|
|
SwissProt
|
Q16539
|
|
Synonyms
|
MAPK14; CSBP;
CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; EXIP; Mxi2; PRKM14; PRKM15; RK; p38;
p38ALPHA
|
|
Category
|
MAP Kinase
Signaling
|
|
Background
|
Mitogen-activated
protein kinase 14, also called p38-α, is an enzyme that
in humans is encoded by the MAPK14 gene. The protein encoded by this gene is
a member of the MAP kinase family. MAP kinases act as an integration point
for multiple biochemical signals, and are involved in a wide variety of
cellular processes such as proliferation, differentiation, transcription
regulation and development. This kinase is activated by various environmental
stresses and proinflammatory cytokines. The activation requires its
phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation
triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The
substrates of this kinase include transcription regulator ATF2, MEF2C, and
MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the
roles of this kinase in stress-related transcription and cell cycle
regulation, as well as in genotoxic stress response.
|
包装清单：
|
产品编号
|
产品名称
|
包装
|
|
XY0222
|
MAPK14 Mouse
Monoclonal Antibody
|
50μl
|
|
XY050
|
Western一抗稀释液
|
50ml
|
|
—
|
说明书
|
1份
|
保存条件：
MAPK14 Mouse
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项：
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10