IKKα Rabbit Polyclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY0198
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IKKα Rabbit Polyclonal Antibody
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50μl
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412.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, FC, IHC,
ICC, IF
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H, M, R
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85KDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:500-1:1000
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-
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1:200
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1:200
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1:200
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1:100-1:200
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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IKKα Rabbit Polyclonal Antibody
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Category
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Polyclonal
antibody(pAb); Primary antibody
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Isotype
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IgG
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Purification
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Peptide XYfinity
purified
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About the
Immunogen
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Immunogen
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This antibody
is produced by immunizing rabbits with a synthetic peptide (KLH-coupled)
corresponding to the N-terminal of IKK alpha.
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Gene ID
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1147
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SwissProt
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O15111
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Synonyms
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CHUK;
conserved helix-loop ubiquitous kinase; Conserved helix-loop-helix ubiquitous
kinase; I-kappa-B kinase 1; I-kappa-B kinase alpha; I-kappa-B kinase-alpha;
IkappaB kinase; IkB kinase alpha subunit; IkBKA; IKK-A; IKK-a kinase;
IKK-alpha; IKK1; IKKA
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Category
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Immunology and
Inflammation
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Background
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Serine kinase
that plays an essential role in the NF-kappa-B signaling pathway which is
activated by multiple stimuli such as inflammatory cytokines, bacterial or
viral products, DNA damages or other cellular stresses. It acts as part of
the canonical IKK complex in the conventional pathway of NF-kappa-B
activation and phosphorylates inhibitors of NF-kappa-B on serine residues.
These modifications allow polyubiquitination of the inhibitors and subsequent
degradation by the proteasome. In turn, free NF-kappa-B is translocated into
the nucleus and activates the transcription of hundreds of genes involved in
immune response, growth control, or protection against apoptosis.
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包装清单：
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产品编号
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产品名称
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包装
|
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XY0198
|
IKKα Rabbit Polyclonal Antibody
|
50μl
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AZ050
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Western一抗稀释液
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50ml
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—
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说明书
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1份
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保存条件：
IKKα Rabbit Polyclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项：
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10