FGFR2/CD332 Mouse Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY0150
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FGFR2/CD332
Mouse Monoclonal Antibody
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50μl
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416.00元
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来源
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用途
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交叉反应性
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分子量
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Mouse
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WB, ICC, IHC,
IF
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H, M
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100,150KDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:500-1:1000
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-
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1:100-1:200
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1:100-1:200
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1:100-1:200
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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FGFR2/CD332
Mouse Monoclonal Antibody
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Category
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Monoclonal
antibody(mAb); Primary antibody
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Isotype
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IgG1
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Purification
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ProA XYfinity
purified
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About the
Immunogen
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Immunogen
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This antibody
is produced by immunizing mice with a recombinant protein corresponding to a
region of FGFR2.
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Gene ID
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2263
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SwissProt
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P21802
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Synonyms
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bacteria-expressed
kinase; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1;
ECT1; FGF receptor; FGFR-2; FGFR2; Fibroblast growth factor receptor 2;
FLJ98662; hydroxyaryl-protein kinase; JWS; K-sam; Keratinocyte growth factor
receptor
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Category
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RTK
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Background
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Fibroblast
growth factor receptor 2 (FGFR2) also known as CD332 has two naturally
occurring isoforms FGFR2IIIb and FGFR2IIIc, created by splicing of the third
immunoglobulin-like domain. FGFR2IIIb is predominantly found in ectoderm
derived tissues and endothelial organ lining, i.e. skin and internal organs.
FGFR2 has important roles in embryonic development and tissue repair,
especially bone and blood vessels. Like the other members of the Fibroblast
growth factor receptor family, these receptors signal by binding to their
ligand and dimerisation (pairing of receptors), which causes the tyrosine
kinase domains to initiate a cascade of intracellular signals. As mentioned,
FGFR2 mutations are associated with craniosynostosis syndromes, which are
skull malformations caused by premature fusion of cranial sutures and other
disease features according to the mutation itself.
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包装清单：
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产品编号
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产品名称
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包装
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XY0150
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FGFR2/CD332
Mouse Monoclonal Antibody
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50μl
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AZ050
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Western一抗稀释液
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50ml
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—
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说明书
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1份
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保存条件：
FGFR2/CD332
Mouse Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项：
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体，包括已经使用过的稀释抗体，请4℃保存。
回收后重复使用的抗体，使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象，可以10,000g离心1-3分钟，取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况，则可以考虑废弃该抗体。
提供的Western一抗稀释液也可以用于**荧光(IF)、**组化(IHC)、**细胞化学(ICC)等适当用途。如果希望获得*佳的检测效果，请考虑使用上述检测专用的一抗稀释液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。