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产品名称: Recombinant Human Bcl-xL
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human Bcl-xL由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human Bcl-xL所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human Bcl-xL
的详细介绍
Recombinant Human Bcl-xL
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产品编号
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产品名称
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产品包装
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产品价格
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XY7248-1mg
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Recombinant
Human Bcl-xL
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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598
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Q07817
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E. coli
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211aa
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23.7kDa
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－
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About this
Antibody
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Name
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Recombinant
Human Bcl-xL (Recombinant Human B-cell Lymphoma-extra Large; rHuBcl-xL)；重组人B细胞**瘤xL
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Synonyms
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Apoptosis
regulator Bcl-X; bcl2-L-1; Bcl2-L-1; BCL2-like 1; bcl-2-like protein 1;
BCLXBCL2LBcl-X; BCLXL; bcl-xL; BCL-XL/S; BCLXS; bcl-xS; DKFZXY781P2092
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Test in
Process.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 20mM Tris-HCl,
pH8.0, 5% Trehalose.
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Endotoxin
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Less than
0.1EU/μg of rHuBcl-xL as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Others
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Background
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Bcl-X, also
named as BCL2L1 or BCL2L, belongs to the Bcl-2 family and it is encoded by
the BCL2L1 gene in human. Alternative splicing of Bcl-X results in at least
two isoforms，isoform Bcl-X(L) (also named as Bcl-xL) and isoform
Bcl-x(S) (also named as Bcl-xS). Bcl-xL is found in tissues containing
long-lived postmitotic cells, such as ***** brain, while Bcl-xS is expressed
at high levels in cells that undergo a high rate of turnover, such as
developing lymphocytes. Bcl-X forms homodimer or heterodimer with other Bcl-2
proteins, like BAK, BAX or Bcl-2, to act as anti- or pro- apoptotic
regulators. Bcl-xL appears to regulate cell death by blocking the
voltage-dependent anion channel (VDAC) by binding to it and preventing the
release of the caspase activator, CYC1, from the mitochondrial membrane, and
it also acts as a regulator of G2 checkpoint and progression to cytokinesis
during mitosis. In contrast, Bcl-xS is a pro-apoptotic protein that promotes
apoptosis.
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Amino Acid
Sequence
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SQSNRELVVD FLSYKLSQKG YSWSQFSDVE
ENRTEAPEGT ESEMETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY
RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIAAWMA
TYLNDHLEPW IQENGGWDTF VELYGNNAAA ESRKGQERFN
R
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包装清单:
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产品编号
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产品名称
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包装
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XY7248-2μg
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Recombinant
Human Bcl-xL
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2μg
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XY7248-10μg
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Recombinant
Human Bcl-xL
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10μg
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XY7248-100μg
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Recombinant
Human Bcl-xL
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100μg
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XY7248-1mg
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Recombinant
Human Bcl-xL
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。