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产品名称: Recombinant Human SYND4
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human SYND4由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human SYND4所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human SYND4
的详细介绍
Recombinant Human SYND4
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产品编号
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产品名称
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产品包装
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产品价格
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XY7172-1mg
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Recombinant
Human SYND4
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1mg
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15611.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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6385
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P31431
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E. coli
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127aa
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13.9kDa
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－
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About this
Antibody
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Name
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Recombinant
Human SYND4 (Recombinant Human Syndecan-4; rHuSYND4)；重组人体聚醣4
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Synonyms
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Amphiglycan;
Ryudocan; SDC4; amphiglycan; Amphiglycan; MGC22217; ryudocan; Ryudocan core
protein; SYND4ryudocan amphiglycan; syndecan 4; syndecan 4 (amphiglycan,
ryudocan); syndecan proteoglycan 4; syndecan-4
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The specific activity is
determined by binding ability in a functional ELISA. Immobilized rHuSYND4 at
500ng/ml (100μl/well) can bind rHubFGF with a linear range of
0.1-10ng/ml.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than
0.1EU/μg of rHuSYND4 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Others
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Background
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Syndecan-4
(SYND4) encoded by the SDC-4 gene in humans, has a molecular weight of
~20kDa. It is one of the four vertebrate syndecans which belong to the
syndecan family of Type 1 transmembrane proteins and capable of carrying
heparin sulfate (HS) and chondroitin sulfate glycosaminoglycans. Syndecans
are the best-characterized plasma membrane proteoglycans with two conserved
cytoplasmic domains and divergent extracellular portions, except for HS
attachment sites. SYND4 is the most similar to SYND2, but is more universally
expressed and is found in virtually every cell type. Expression can be
upregulated by TGFβ2 and in response to mechanical stress in smooth
muscle, wound healing, arterial injury or acute myocardial infarction,
probably in response to at least one inflammatory mediator. SYND4 has more
widespread distribution than other syndecans and it is the only syndecan that
has been found consistently in focal adhesions. Human SYND4 ECD shares
approximately 79%, 78% and 81%a.a. identity with mouse, rat and porcine SYND4
ECD, respectively.
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Amino Acid
Sequence
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ESIRETEVID PQDLLEGRYF SGALPDDEDV
VGPGQESDDF ELSGSGDLDD LEDSMIGPEV VHPLVPLDNH IPERAGSGSQ VPTEPKKLEE NEVIPKRISP
VEESEDVSNK VSMSSTVQGS NIFERTE
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包装清单:
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产品编号
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产品名称
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包装
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XY7172-5μg
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Recombinant
Human SYND4
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5μg
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XY7172-25μg
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Recombinant
Human SYND4
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25μg
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XY7172-100μg
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Recombinant
Human SYND4
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100μg
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XY7172-1mg
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Recombinant
Human SYND4
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。