Recombinant Human Neuroserpin
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产品名称: Recombinant Human Neuroserpin
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human Neuroserpin由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human Neuroserpin所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human Neuroserpin
的详细介绍
Recombinant Human Neuroserpin
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产品编号
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产品名称
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产品包装
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产品价格
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XY7032-1mg
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Recombinant
Human Neuroserpin
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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5274
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Q99574
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E. coli
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394aa
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44.7kDa
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－
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About this
Antibody
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Name
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Recombinant
Human Neuroserpin (Recombinant Human Neuroserpin; rHuNeuroserpin)；重组人Neuroserpin蛋白
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Synonyms
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Neuroserpin;
PI12; DKFZXY781N13156; neuroserpin; Peptidase inhibitor 12; PI-12; PI12Serpin
I1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member
1; serpin peptidase inhibitor, clade I (neuroserpin), member 1
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using rat C6 cells is less than 0.5μg/ml, corresponding to a specific activity of >2000IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuNeuroserpin as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Enzymes
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Background
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Neuroserpin
encoded by the SERPINI1 gene in humans is a member of the serine proteinase
inhibitor (serpin) family. It reacts preferentially with tissue-type
plasminogen activator (tPA). Neuroserpin is expressed mainly in the central
nervous system (CNS) in response to neuronal depolarization and plays an
important role in the development of synaptic plasticity. Mutations in human
neuroserpin result in a form of autosomal dominant inherited dementia which
is characterized by the presence of intraneuronal inclusion bodies and is
known as Familial Encephalopathy with Neuroserpin Inclusion Bodies.
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Amino Acid
Sequence
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TGATFPEEAI ADLSVNMYNR LRATGEDENI
LFSPLSIALA MGMMELGAQG STQKEIRHSM GYDSLKNGEE FSFLKEFSNM VTAKESQYVM KIANSLFVQN
GFHVNEEFLQ MMKKYFNAAV NHVDFSQNVA VANYINKWVE NNTNNLVKDL VSPRDFDAAT YLALINAVYF
KGNWKSQFRP ENTRTFSFTK DDESEVQIPM MYQQGEFYYG EFSDGSNEAG GIYQVLEIPY EGDEISMMLV
LSRQEVPLAT LEPLVKAQLV EEWANSVKKQ KVEVYLPRFT VEQEIDLKDV LKALGITEIF IKDANLTGLS
DNKEIFLSKA IHKSFLEVNE EGSEAAAVSG MIAISRMAVL YPQVIVDHPF FFLIRNRRTG TILFMGRVMH
PETMNTSGHD FEEL
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包装清单:
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产品编号
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产品名称
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包装
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XY7032-5μg
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Recombinant
Human Neuroserpin
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5μg
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XY7032-25μg
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Recombinant
Human Neuroserpin
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25μg
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XY7032-100μg
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Recombinant
Human Neuroserpin
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100μg
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XY7032-1mg
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Recombinant
Human Neuroserpin
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。