Recombinant Human SDF-1α/CXCL12α
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产品名称: Recombinant Human SDF-1α/CXCL12α
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human SDF-1α/CXCL12α由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human SDF-1α/CXCL12α所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human SDF-1α/CXCL12α
的详细介绍
Recombinant Human SDF-1α/CXCL12α
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产品编号
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产品名称
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产品包装
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产品价格
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XY6537-1mg
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Recombinant
Human SDF-1α/CXCL12α
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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6387
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P48061
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E. coli
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68aa
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8.0kDa
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－
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About this
Antibody
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Name
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Recombinant
Human SDF-1α/CXCL12α (Recombinant Human
Stromal-Cell Derived Factor-1α/CXCL12α; rHuSDF-1α/CXCL12α)；重组人基质细胞衍生因子1α/CXCL12α
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Synonyms
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CXCL12
chemokine (C-X-C motif) ligand 12; IRH; PBSF; SCYB12; SDF1; SDF1A; SDF1B;
TLSF; TPAR1
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The biological activity
determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human
peripheral blood T-lymphocytes is in a concentration range of 20-80ng/ml.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μM filtered concentrated solution in 20mM PB pH7.0,
130mM NaCl.
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Endotoxin
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Less than 1EU/μg of rHuSDF-1α/CXCL12α as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Chemokines
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Background
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CXCL12 also
known as SDF-1 is belonging to the CXC chemokine family. It is encoded by the
CXCL12 gene. In recently study, Human CXCL12 is expressed as six isoforms
that differ only in the C-terminal tail. And all SDF-1 isoforms undergo
proteolytic processing of the first two N-terminal amino acids. Contrast to
the canonical sequence SDF-1β, SDF-1α is
shorter by four amino acids at the C-terminal tail. On the cell surface, the
receptor for this chemokine is CXCR4 and syndecan4. CXCL12 is strongly
chemotactic for T-lymphocytes, monocytes, but not neutrophils. CXCL12 is a
very important factor in carcinogenesis and the neovascularisation linked to
tumor progression.
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Amino Acid
Sequence
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KPVSLSYRCP CRFFESHVAR ANVKHLKILN
TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
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包装清单:
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产品编号
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产品名称
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包装
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XY6537-2μg
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Recombinant
Human SDF-1α/CXCL12α
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2μg
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XY6537-10μg
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Recombinant
Human SDF-1α/CXCL12α
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10μg
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XY6537-100μg
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Recombinant
Human SDF-1α/CXCL12α
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100μg
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XY6537-1mg
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Recombinant
Human SDF-1α/CXCL12α
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。