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产品名称: Recombinant Rat IL-17A
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Rat IL-17A由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Rat IL-17A所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Rat IL-17A
的详细介绍
Recombinant Rat IL-17A
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产品编号
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产品名称
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产品包装
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产品价格
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XY6303-1mg
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Recombinant
Rat IL-17A
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1mg
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15611.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Rat
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301289
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G3V7M4
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E. coli
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133aa
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30kDa
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－
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About this
Antibody
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Name
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Recombinant
Rat IL-17A (Recombinant Rat Interleukin-17A; rRtIL-17A)；重组大鼠白细胞介素17A
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Synonyms
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CTLA-8; IL17A;
CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic
T-lymphocyte-associated antigen 8; IL-17Acytotoxic T-lymphocyte-associated
protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic
T-lymphocyte-associated serine esterase 8); interleukin 17A
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by
inducing IL-6 secretion of murine NIH/3T3 cells is less than 1.0ng/ml,
corresponding to a specific activity of >1.0×106IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 2X PBS, pH6.5.
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Endotoxin
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Less than
0.1EU/μg of rRtIL-17A as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in 4mM HCl to a concentration of 0.1-1.0mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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IL-17A, also
named CTLA8 and IL17, is belonging to the IL-17 family and is encoded by the
IL-17A gene in humans. The IL-17 family is comprised of at least six
proinflammatory cytokines that share a conserved cysteine-knot structure but
diverge at the N-terminus. This cytokine regulates the activities of
NF-kappaB and mitogen-activated protein kinases, and can stimulate the
expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the
production of nitric oxide (NO). IL-17 family members are glycoproteins
secreted as dimers that induce local cytokine production and recruit
granulocytes to sites of inflammation.
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Amino Acid
Sequence
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AVLIPQSSVC PNAEANNFLQ NVKVNLKVIN
SLSSKASSRR PSDYLNRSTS PWTLSRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL
KREPEKCPFT FRVEKMLVGV GCTCVSSIVR HAS
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包装清单:
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产品编号
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产品名称
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包装
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XY6303-5μg
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Recombinant
Rat IL-17A
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5μg
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XY6303-25μg
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Recombinant
Rat IL-17A
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25μg
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XY6303-100μg
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Recombinant
Rat IL-17A
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100μg
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XY6303-1mg
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Recombinant
Rat IL-17A
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。