Recombinant Murine IFN-λ2/IL-28A
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产品名称: Recombinant Murine IFN-λ2/IL-28A
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Murine IFN-λ2/IL-28A由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine IFN-λ2/IL-28A所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Murine IFN-λ2/IL-28A
的详细介绍
Recombinant Murine IFN-λ2/IL-28A
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产品编号
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产品名称
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产品包装
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产品价格
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XY6141-1mg
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Recombinant
Murine IFN-λ2/IL-28A
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Mouse
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330496
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Q4VK74
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E. coli
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174aa
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19.7kDa
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－
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About this
Antibody
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Name
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Recombinant
Murine IFN-λ2/IL-28A (Recombinant Murine Interferon-λ2/Interleukin-28A; rMuIFN-λ2/IL-28A)；Recombinant Mouse IFN-λ2/IL-28A ; 重组小鼠干扰素λ2/白细胞介素28A
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Synonyms
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IFN-lambda 2;
interleukin-28A; IL28A; IL-28A; interferon, lambda 2
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by an
anti-viral assay using human HepG2 cells infected with encephalomyocarditis
is less than 3ng/ml, corresponding to a specific activity of >3.3×105IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4, with
5% trehalose.
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Endotoxin
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Less than
0.1EU/μg of rMuIFN-λ2/IL-28A as
determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interferon
lambda-2, as known as IL-28A, belongs to the lambda interferon family. IL-28A
(IFN-λ2), IL-28B (IFN-λ3) and IL-29
(IFN-λ1) are type III interferons that are class II
cytokine receptor ligands. These IFNs signal through a receptor complex
consisting of IL10R2 (also called CRF2-4) and IFNLR1 (also called CRF2-12).
Interferon lambda-2 displays potent antiviral activity and antitumor
activity, so it plays a significant role in the antiviral immune defense in
the intestinal epithelium. It also upregulate MHC class I antigen expression.
Recombinant murine interferon lambda-2 contains 174 amino acids and it shares
81% and 66%a.a. sequence identity with rat and human IFN-λ2, respectively, and functions across species.
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Amino Acid
Sequence
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DPVPRATRLP VEAKDCHIAQ FKSLSPKELQ
AFKKAKDAIE KRLLEKDMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENMTDS ALATILGQPL
HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQEAQ SKETPGCLED SVTSNLFRLL TRDLKCVASG
DQCV
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包装清单:
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产品编号
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产品名称
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包装
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XY6141-5μg
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Recombinant
Murine IFN-λ2/IL-28A
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5μg
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XY6141-20μg
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Recombinant
Murine IFN-λ2/IL-28A
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20μg
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XY6141-100μg
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Recombinant
Murine IFN-λ2/IL-28A
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100μg
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XY6141-1mg
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Recombinant
Murine IFN-λ2/IL-28A
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。