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产品名称: Recombinant Murine IFN-γ
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Murine IFN-γ由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine IFN-γ所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Murine IFN-γ
的详细介绍
Recombinant Murine IFN-γ
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产品编号
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产品名称
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产品包装
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产品价格
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XY6137-1mg
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Recombinant
Murine IFN-γ
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1mg
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5665.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Mouse
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15978
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P01580
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E. coli
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133aa
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15.5kDa
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－
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About this
Protein
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Name
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Recombinant
Murine IFN-γ (Recombinant Murine Interferon-γ; rMuIFN-γ)；Recombinant Mouse IFN-γ ; 重组小鼠干扰素γ
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Synonyms
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IFNG; IFG;
IFI; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma
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Purity
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>96% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by an
anti-viral assay using murine L929 cells infected with encephalomyocarditis
(EMC) virus is less than 0.8ng/ml, corresponding to a specific activity of
>1.3×106IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered solution in PBS, pH7.4, containing 5%
trehalose.
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Endotoxin
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Less than 1EU/μg of rMuIFN-γ as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interferon-gamma
(IFN-γ), also known as Type II interferon or immune
interferon, is a cytokine produced primarily by Tlymphocytes and natural
killer cells. The protein shares no significant homology with IFN-β or the various IFN-α family proteins.
Mature IFN-γ exists as noncovalently-linked
homodimers. It shares high sequence indentity with rat IFN-γ (86%). IFN-γ was originally characterized
based on its antiviral activities. The protein also exerts antiproliferative,
immunoregulatory and proinflammatory activities and is thus important in host
defense mechanisms. IFN-γ induces the production of
cytokines, upregulates the expression of class I and II MHC antigens, Fc
receptor and leukocyte adhesion molecules. It modulates macrophage effector
functions, influences isotype switching and potentiates the secretion of
immunoglobulins by B cells. Additionally, IFN-γ augments TH1 cell expansion and may be required for TH1 cell differentiation.
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Amino Acid
Sequence
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HGTVIESLES LNNYFNSSGI DVEEKSLFLD
IWRNWQKDGD MKILQSQIIS FYLRLFEVLK DNQAISNNIS VIESHLITTF FSNSKAKKDA FMSIAKFEVN
NPQVQRQAFN ELIRVVHQLL PESSLRKRKR SRC
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包装清单:
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产品编号
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产品名称
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包装
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XY6137-20μg
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Recombinant
Murine IFN-γ
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20μg
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XY6137-100μg
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Recombinant
Murine IFN-γ
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100μg
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XY6137-1mg
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Recombinant
Murine IFN-γ
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。