Recombinant Murine sTNF RII/TNFRSF1B
如果您对该产品感兴趣的话,可以
产品名称: Recombinant Murine sTNF RII/TNFRSF1B
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Murine sTNF RII/TNFRSF1B由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine sTNF RII/TNFRSF1B所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Murine sTNF RII/TNFRSF1B
的详细介绍
Recombinant Murine sTNF RII/TNFRSF1B
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY6065-1mg
|
Recombinant
Murine sTNF RII/TNFRSF1B
|
1mg
|
15611.00元
|
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Mouse
|
21938
|
P25119
|
E. coli
|
236aa
|
25.3kDa
|
-
|
|
About this
Antibody
|
|
Name
|
Recombinant
Murine sTNF RII/TNFRSF1B (Recombinant Murine soluble Tumor Necrosis Factor
Receptor Type II/TNFRSF1B; rMusTNF RII/TNFRSF1B);Recombinant Mouse sTNF RII/TNFRSF1B ; 重组小鼠可溶性肿瘤坏死因子受体II型/TNFRSF1B
|
|
Synonyms
|
CD120b;
TNFRSF1B; CD120b; CD120b antigen; Etanercept; p75 TNF receptor; p75TBPII;
p75TNFR; soluble TNFR1B variant 1; TNFBRp80 TNF-alpha receptor; TNF-R2;
TNFR2TNFR1B; TNF-R75; TNFR80; TNF-RII; TNF-R-II; TNFR-II; tumor necrosis
factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis
factor receptor 2; tumor necrosis factor receptor superfamily member 1B;
tumor necrosis factor receptor superfamily, member 1B; Tumor necrosis factor
receptor type II
|
|
Purity
|
>97% by
SDS-PAGE and HPLC analyses.
|
|
Biological
Activity
|
Fully
biologically active when compared to standard. The ED50 as determined by its
ability to inhibit the TNF-α mediated cytotoxicity in the L-929
cells is less than 2μg/ml, corresponding to a
specific activity of >500IU/mg in the presence of 0.1ng/ml of rMuTNF-α.
|
|
Physical
Appearance
|
Sterile
Filtered White lyophilized (freeze-dried) powder.
|
|
Formulation
|
Lyophilized
from a 0.2μm filtered solution in PBS, pH7.4.
|
|
Endotoxin
|
Less than
0.1EU/μg of rMusTNF RII/TNFRSF1B as determined by LAL method.
|
|
Reconstitution
|
We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
|
|
Category
|
Cytokine
|
|
Background
|
TNFRSF1B also
known as tumor necrosis factor receptor 2 (TNFR2) and CD120b, is encoded by
the TNFRSF1B gene in humans. It is a member of the tumor necrosis factor
receptor superfamily, which also contains TNFRSF1A. This protein and
TNF-receptor 1 form a heterocomplex that mediates the recruitment of two
anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase
activity. TNFRSF1B has been shown to interact with TRAF2 and TTRAP.
Recombinant murine TNFRSF1B is a 25.3kDa protein with 236 amino acid
residues.
|
|
Amino Acid
Sequence
|
VPAQVVLTPY KPEPGYECQI SQEYYDRKAQ
MCCAKCPPGQ YVKHFCNKTS DTVCADCEAS MYTQVWNQFR TCLSCSSSCT TDQVEIRACT KQQNRVCACE
AGRYCALKTH SGSCRQCMRL SKCGPGFGVA SSRAPNGNVL CKACAPGTFS DTTSSTDVCR PHRICSILAI
PGNASTDAVC APESPTLSAI PRTLYVSQPE PTRSQPLDQE PGPSQTPSIL TSLGSTPIIE QSTKGG
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY6065-5μg
|
Recombinant
Murine sTNF RII/TNFRSF1B
|
5μg
|
|
XY6065-20μg
|
Recombinant
Murine sTNF RII/TNFRSF1B
|
20μg
|
|
XY6065-100μg
|
Recombinant
Murine sTNF RII/TNFRSF1B
|
100μg
|
|
XY6065-1mg
|
Recombinant
Murine sTNF RII/TNFRSF1B
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
为了您的**和健康,请穿实验服并戴一次性手套操作。