Recombinant Murine IL-36 Receptor Antagonist
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产品名称: Recombinant Murine IL-36 Receptor Antagonist
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Murine IL-36 Receptor Antagonist由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine IL-36 Receptor Antagonist所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Murine IL-36 Receptor Antagonist
的详细介绍
Recombinant Murine IL-36 Receptor Antagonist
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产品编号
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产品名称
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产品包装
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产品价格
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XY5993-1mg
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Recombinant
Murine IL-36 Receptor Antagonist
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1mg
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15611.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Mouse
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54450
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Q9QYY1
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E. coli
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154aa
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16.9kDa
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－
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About this
Antibody
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Name
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Recombinant
Murine IL-36 Receptor Antagonist (Recombinant Murine Interleukin-36 Receptor
Antagonist Protein ; rMuIL-36RA)；Recombinant Mouse IL-36 Receptor Antagonist ; 重组小鼠白细胞介素36受体拮抗剂
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Synonyms
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FIL1 delta;
IL1F5; IL-1HY1; IL-1L1; IL-1RP3; IL36RN; IL36RA; IL-36RA; Interleukin 36
Receptor Antagonist; Interleukin-36 Receptor Antagonist
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Measured by
its ability to inhibit IL-36γ induced IL-6 production by human
PBMCs.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rMuIL-36RA as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interleukin-36
receptor antagonist (IL-36RA) is a secreted protein which belongs to the
interleukin 1 cytokine family (IL-1 family) and it is predominantly expressed
in keratinocytes but not in fibroblasts, endothelial cells or
melanocytes.IL-36RA has been reported to antagonize the biological activity
of IL-36α (IL-1F6), IL-36β (IL-1F8),
and IL-36γ (IL-1F9). Furthermore, it could constitute
part of an independent signaling system analogous to interleukin-1 alpha
(IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I
(IL-1R1). In addition, The receptor for IL-36RA has not been positively
identified. Indirect evidence suggests it is IL-1Rrp2. Recombinant murine
interleukin-36 RA contains 154 amino acid residues and it shares 91%a.a.
sequence identity with human IL-36RA.
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Amino Acid
Sequence
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VLSGALCFRM KDSALKVLYL HNNQLLAGGL
HAEKVIKGEE ISVVPNRALD ASLSPVILGV QGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY
RRDMGLTSSF ESAAYPGWFL CTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD
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包装清单:
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产品编号
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产品名称
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包装
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XY5993-2μg
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Recombinant
Murine IL-36 Receptor Antagonist
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2μg
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XY5993-10μg
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Recombinant
Murine IL-36 Receptor Antagonist
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10μg
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XY5993-100μg
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Recombinant
Murine IL-36 Receptor Antagonist
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100μg
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XY5993-1mg
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Recombinant
Murine IL-36 Receptor Antagonist
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。