Recombinant Murine IL-36α, 160a.a.
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产品名称: Recombinant Murine IL-36α, 160a.a.
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Murine IL-36α, 160a.a.由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine IL-36α, 160a.a.所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Murine IL-36α, 160a.a.
的详细介绍
Recombinant Murine IL-36α, 160a.a.
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产品编号
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产品名称
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产品包装
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产品价格
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XY5975-1mg
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Recombinant
Murine IL-36α, 160a.a.
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1mg
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27053.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Mouse
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54448
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Q9JLA2
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E. coli
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160aa
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18kDa
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－
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About this
Antibody
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Name
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Recombinant
Murine IL-36α, 160a.a. (Recombinant Murine Interleukin-36α, 160a.a.; rMuIL-36α, 160a.a.)；Recombinant Mouse IL-36α, 160a.a. ; 重组小鼠白细胞介素36α，160a.a.
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Synonyms
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FIL1 epsilon;
IL-1E; IL1F6; IL36A; FIL1; FIL1 epsilon; FIL1(EPSILON); FIL1E; IL-1 epsilon;
IL1(EPSILON); IL1E; IL1F6; IL-1F6; IL-1F6 (FIL-1-epsilon); interleukin 1
family, member 6 (epsilon); interleukin 1, epsilon; Interleukin 36, Alpha;
Interleukin-1 epsilon; interleukin-1 family member 6; Interleukin-36 Alpha
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The specific activity
determined by its ability in a functional ELISA. Immobilized rMuIL-36α at 1μg/ml can bind recombinant murine
IL-1 Rrp2 with a range of 0.15-5μg/ml.
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Physical
Appearance
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Sterile Filtered
White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4, 5%
trehalose.
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Endotoxin
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Less than 1EU/μg of rMuIL-36α, 160a.a. as determined by
LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interleukin-36
(IL-36) is a pro-inflammatory cytokine which plays an important role in the
pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and
IL-1F9) are IL-1 family members that signal through the IL-1 receptor family
members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36α is
mainly found in skin and lymphoid tissues, but also in fetal brain, trachea,
stomach and intestine. It is expressed by monocytes, B and T cells. Notably,
IL-36 alpha is the only novel IL-1 family member expressed on T-cells.
Recombinant murine interleukin-36 alpha contains 160 amino acids residues
which is a single nonglycosylated polypeptide. Specifically, mouse IL-36α shares 83%a.a. sequence identity with rat IL-36α, 54-60% with human, rabbit, equine and bovine IL-36α.
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Amino Acid
Sequence
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MNKEKELRAA SPSLRHVQDL SSRVWILQNN
ILTAVPRKEQ TVPVTITLLP CQYLDTLETN RGDPTYMGVQ RPMSCLFCTK DGEQPVLQLG EGNIMEMYNK
KEPVKASLFY HKKSGTTSTF ESAAFPGWFI AVCSKGSCPL ILTQELGEIF ITDFEMIVVH
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包装清单:
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产品编号
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产品名称
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包装
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XY5975-2μg
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Recombinant
Murine IL-36α, 160a.a.
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2μg
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XY5975-10μg
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Recombinant
Murine IL-36α, 160a.a.
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10μg
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XY5975-100μg
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Recombinant
Murine IL-36α, 160a.a.
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100μg
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XY5975-1mg
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Recombinant
Murine IL-36α, 160a.a.
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。