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产品名称: Recombinant Murine IL-11
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Murine IL-11由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine IL-11所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Murine IL-11
的详细介绍
Recombinant Murine IL-11
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产品编号
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产品名称
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产品包装
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产品价格
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XY5943-1mg
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Recombinant
Murine IL-11
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1mg
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26773.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Mouse
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16156
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P47873
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E. coli
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179aa
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19.1kDa
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－
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About this
Antibody
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Name
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Recombinant
Murine IL-11 (Recombinant Murine Interleukin-11; rMuIL-11)；Recombinant Mouse IL-11 ; 重组小鼠白细胞介素11
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Synonyms
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AGIF;
Adipogenesis inhibitory factor; AGIFoprelvekin; IL-11Oprelvekin; interleukin
11; interleukin-11
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using murine T11 cells is less than 2ng/ml,
corresponding to a specific activity of >5.0×105IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rMuIL-11 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interleukin-11
(IL-11) is encoded by the IL11 gene. IL-11 is a multifunctional cytokine
first isolated from bone marrow-derived stromal cells. IL-11 receptor
activation requires formation of a complex of two IL-11 molecules with two
molecules of the ligand-binding IL-11 Rα subunit and two
molecules of the expressed cell signaling β subunit,
gp130. IL-11 is a member of the IL-6 superfamily, distinguished based on
their use of the common co-receptor gp130. IL-11 can directly stimulate the
proliferation of hematopoietic stem cells and megakaryocyte progenitor cells,
and induce megakaryocyte maturation resulting in increased platelet
production. Mature murine IL-11 shares 88% amino acid sequence identity with
human IL-11.
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Amino Acid
Sequence
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MPGPPAGSPR VSSDPRADLD SAVLLTRSLL
ADTRQLAAQM RDKFPADGDHSLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW
LRRAGGPSLKTLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGSIRAAHAILGG
LHLTLDWAVR GLLLLKTRL
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包装清单:
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产品编号
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产品名称
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包装
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XY5943-2μg
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Recombinant
Murine IL-11
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2μg
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XY5943-10μg
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Recombinant
Murine IL-11
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10μg
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XY5943-100μg
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Recombinant
Murine IL-11
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100μg
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XY5943-1mg
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Recombinant
Murine IL-11
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。