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产品名称: Recombinant Murine IL-2
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Murine IL-2由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine IL-2所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Murine IL-2
的详细介绍
Recombinant Murine IL-2
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产品编号
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产品名称
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产品包装
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产品价格
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XY5907-1mg
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Recombinant
Murine IL-2
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1mg
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14411.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Mouse
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16183
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P04351
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E. coli
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149aa
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17.2kDa
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－
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About this
Antibody
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Name
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Recombinant
Murine IL-2 (Recombinant Murine Interleukin-2; rMuIL-2)；Recombinant Mouse IL-2 ; 重组小鼠白细胞介素2
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Synonyms
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aldesleukin;
Aldesleukin; IL-2lymphokine; interleukin 2; interleukin-2; involved in
regulation of T-cell clonal expansion; T cell growth factor; T-cell growth
factor; TCGF
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using murine CTLL-2 cells is less than 0.2ng/ml,
corresponding to a specific activity of >5.0×106IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rMuIL-2 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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IL-2 is a
powerful immunoregulatory lymphokine produced by T-cells in response to
antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R
signaling is required for T cell proliferation and other fundamental
functions which are essential for the immune response. The receptor for IL-2
consists of three subunits (55kDa IL-2Rα, 75kDa IL-2Rβ, 64kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed
complexes. Mature mouse IL-2 shares 56% and 73% amino acid sequence identity
with human and rat IL-2 respectively. Mouse and human IL-2 exhibit
cross-species activity. Mouse IL-2 has a specific N-terminal region that
contains a poly glutamine (contain 12 glutamines) stretch.
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Amino Acid
Sequence
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APTSSSTSSS TAEAQQQQQQ QQQQQQHLEQ
LLMDLQELLS RMENYRNLKL PRMLTFKFYL PKQATELKDL QCLEDELGPL RHVLDLTQSK SFQLEDAENF
ISNIRVTVVK LKGSDNTFEC QFDDESATVV DFLRRWIAFC QSIISTSPQ
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包装清单:
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产品编号
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产品名称
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包装
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XY5907-5μg
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Recombinant
Murine IL-2
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5μg
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XY5907-20μg
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Recombinant
Murine IL-2
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20μg
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XY5907-100μg
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Recombinant
Murine IL-2
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100μg
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XY5907-1mg
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Recombinant
Murine IL-2
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。