如果您对该产品感兴趣的话,可以
产品名称: Recombinant Human BD-2
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human BD-2由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human BD-2所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human BD-2
的详细介绍
Recombinant Human BD-2
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY5804-1mg
|
Recombinant
Human BD-2
|
1mg
|
15444.00元
|
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Human
|
1673
|
O15263
|
E. coli
|
41aa
|
4.3kDa
|
－
|
|
About this
Antibody
|
|
Name
|
Recombinant
Human BD-2 (Recombinant Human β-defensin 2; rHuBD-2)；重组人β-防御素2
|
|
Synonyms
|
BD-2; DEFB2;
DEFB4A; DEFB4B; HBD-2; SAP-1; Beta-defensin 2; DEFB-2; DEFB2DEFB102;
DEFB4beta-defensin 4A; Defensin, beta 2Skin-antimicrobial peptide 1;
defensin, beta 4; defensin, beta 4A; HBD-2; hBD-2; SAP1BD-2
|
|
Purity
|
>98% by
SDS-PAGE and HPLC analyses.
|
|
Biological
Activity
|
Fully
biologically active when compared to standard. The biological activity
determined by a chemotaxis bioassay using immature human dendritic cells is
in a concentration range of 10-100ng/ml.
|
|
Physical
Appearance
|
Sterile
Filtered White lyophilized (freeze-dried) powder.
|
|
Formulation
|
Lyophilized
from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4,
130mM NaCl.
|
|
Endotoxin
|
Less than 1EU/μg of rHuBD-2 as determined by LAL method.
|
|
Reconstitution
|
We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
|
|
Category
|
Cytokine
|
|
Background
|
Defensins
(alpha and beta) are cationic peptides with antimicrobial activity against
Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses. They
are 2-6kDa proteins and take important roles in innate immune system. On the
basis of their size and pattern of disulfide bonding, mammalian defensins are
classified into alpha, beta and theta categories. β-Defensins contain a six-cysteine motif that forms three
intra-molecular disulfide bonds. Four human β-defensins
have been identified and they are expressed on some leukocytes and at
epithelial surfaces. Because β-defensins is cationic
peptides, they can therefore interact with the membrane of invading microbes,
which are negative due to lipopolysaccharides (LPS) and lipoteichoic acid
(LTA) found in the cell membrane. Especially, they have higher affinity to
the binding site compared to Ca2+ and Mg2+ ions. Furthermore, they can affect the
stability of the membrane.
|
|
Amino Acid
Sequence
|
GIGDPVTCLK SGAICHPVFC PRRYKQIGTC
GLPGTKCCKK P
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY5804-5μg
|
Recombinant
Human BD-2
|
5μg
|
|
XY5804-20μg
|
Recombinant
Human BD-2
|
20μg
|
|
XY5804-100μg
|
Recombinant
Human BD-2
|
100μg
|
|
XY5804-1mg
|
Recombinant
Human BD-2
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。