如果您对该产品感兴趣的话,可以
产品名称: Recombinant Human BMP-2
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human BMP-2由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human BMP-2所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human BMP-2
的详细介绍
Recombinant Human BMP-2
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY5754-1mg
|
Recombinant
Human BMP-2
|
1mg
|
27053.00元
|
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Human
|
650
|
P12643
|
E. coli
|
115aa
|
26kDa
|
－
|
|
About this
Antibody
|
|
Name
|
Recombinant
Human BMP-2 (Recombinant Human Bone Morphogenetic Protein 2; rHuBMP-2)；重组人骨形态发生蛋白2
|
|
Synonyms
|
BMP-2; BMP-2A;
BMP2ABone morphogenetic protein 2A; bone morphogenetic protein 2
|
|
Purity
|
>95% by
SDS-PAGE and HPLC analyses.
|
|
Biological
Activity
|
Fully
biologically active when compared to standard. The ED50 as determined by
inducing alkaline phosphatase production of murine ATDC5 cells is less than
200ng/ml, corresponding to a specific activity of >5.0×103IU/mg.
|
|
Physical Appearance
|
Sterile
Filtered White lyophilized (freeze-dried) powder.
|
|
Formulation
|
Lyophilized
from a 0.2μm filtered concentrated solution containing 10mM
sodium citrate pH3.5.
|
|
Endotoxin
|
Less than 1EU/μg of rHuBMP-2 as determined by LAL method.
|
|
Reconstitution
|
We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled H2O to a
concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into
working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered
solutions. Do not reconstitute in PBS or cell culture media.
|
|
Category
|
Cytokine
|
|
Background
|
Bone
Morphogenetic Protein 2 is one of the BMPs, some of which belong to the
TGF-beta superfamily (BMP2-7). There are more than thirteen BMPs have been
discovered nowadays and they are involved in inducing cartilage and bone
formation. BMP-2 is expressed in a variety of tissues including lung, spleen,
brain, liver, prostate ovary and small intestine. It is a potent
osteoinductive cytokine and plays its role in association with
osteoconductive carriers such as collagen and synthetic hydroxyapatite. As it
shown to stimulate the production of bone, the recombinant human BMP-2 is
available for orthopaedic usage and dentisty. The functional form of BMP-2 is
a disulflde-linked homodimer and about 26kDa The precursor of BMP-2 is
259a.a., containing the 23a.a. Nterminal signal sequence which will be
cleaved by a furin-type protease to form the mature peptide.
|
|
Amino Acid
Sequence
|
MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN
DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV
LKNYQDMVVE GCGCR
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY5754-2μg
|
Recombinant
Human BMP-2
|
2μg
|
|
XY5754-10μg
|
Recombinant
Human BMP-2
|
10μg
|
|
XY5754-100μg
|
Recombinant
Human BMP-2
|
100μg
|
|
XY5754-1mg
|
Recombinant
Human BMP-2
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。