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产品名称: Recombinant Human NT-4
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human NT-4由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human NT-4所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human NT-4
的详细介绍
Recombinant Human NT-4
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产品编号
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产品名称
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产品包装
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产品价格
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XY5678-1mg
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Recombinant
Human NT-4
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1mg
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26773.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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4909
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P34130
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E. coli
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262aa
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28.1kDa
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－
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About this
Antibody
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Name
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Recombinant
Human NT-4 (Recombinant Human Neurotrophin-4; rHuNT-4)；重组人神经营养因子4
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Synonyms
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NT-5; NTF4;
NTF5; GLC10; GLC1O; neurotrophic factor 4; neurotrophic factor 5;
neurotrophin 4; neurotrophin 5 (neurotrophin 4/5); neurotrophin-4;
Neurotrophin-5; neurotrophin-5; Neutrophic factor 4; NT4; NT-4; NT-4/5; NT-5;
NTF5NT5
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by the
dose-dependent induction of choline acetyl transferase activity in rat basal
forebrain primary septal cell cultures is less than 50ng/ml, corresponding to
a specific activity of >2.0×104IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH5.5.
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Endotoxin
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Less than 1EU/μg of rHuNT-4 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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NT-4 also
named as NT-5 is a neuronal and epithelial grow factor belongs to thengF-beta
family. The NT-4 precursor is consisted of a 24a.a. signal peptide, a 56a.a.
propertied and 130a.a. NT-4. The mature protein has six Cys amino acid
residues and has the relative structure with NT-3, BDNF (sharing about
48%-52% sequence identity). Additionally, it shares 91% and 95%a.a. sequence
identity with mouse and rat NT-4. NT-4 is mainly expressed in prostate and
has low level thymus, placenta, and skeletal muscle. It can binding with the
LNGFR and trkB receptors and plays a crucial role in the regulation of
survival and the maintenance of peripheral sensory sympathetic neurons.
Defect of NT-4 may cause primary open angle glaucoma type 1O.
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Amino Acid
Sequence
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MGVSETAPAS RRGELAVCDA VSGWVTDRRT
AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA
LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A
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包装清单:
|
产品编号
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产品名称
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包装
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XY5678-2μg
|
Recombinant
Human NT-4
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2μg
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XY5678-10μg
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Recombinant
Human NT-4
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10μg
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XY5678-100μg
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Recombinant
Human NT-4
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100μg
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|
XY5678-1mg
|
Recombinant
Human NT-4
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1mg
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|
-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。