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产品名称: Recombinant Human IFN-ω
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human IFN-ω由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human IFN-ω所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human IFN-ω
的详细介绍
Recombinant Human IFN-ω
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产品编号
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产品名称
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产品包装
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产品价格
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XY5673-1mg
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Recombinant
Human IFN-ω
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1mg
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5718.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3467
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P05000
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E. coli
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172aa
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20kDa
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－
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About this
Protein
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Name
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Recombinant
Human IFN-ω (Recombinant Human Interferon-ω; rHuIFN-ω)；重组人干扰素ω
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Synonyms
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IFNW1;
IFN-omega 1, interferon omega-1; Interferon alpha-II-1; interferon omega-1;
interferon, omega 1
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
chemotaxis bioassay using human TF-1 cells is less than 0.01ng/ml,
corresponding to a specific activity of >1.0×108IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuIFN-ω as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interferon-Omega
(IFN-ω) coded by IFNW1 gene in human, is a number of the
type I interferon family, which includes IFN-α, IFN-β, and IFN-ω. The IFNAR-1/IFNAR-2 receptor
complex can help with the signal transduction, followed the antiviral or the
antiproliferative actions. IFN-ω is derived from IFN-α/β and share 75% sequence with IFN-α. It has two intramolecular disulfide bonds which are crucial for
activities. Mire-Sluis et al have described bioassays for IFN-α, IFN-β, and IFN-ω that exploit the ability of these factors to inhibit proliferation of TF-1
cells induced by GM-CSF. The bioassays can be used also with Epo and TF-1
cells, or Epo and Epo-transfected UT-7 cells.
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Amino Acid
Sequence
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CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL
KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL
LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG
SS
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包装清单:
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产品编号
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产品名称
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包装
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XY5673-20μg
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Recombinant
Human IFN-ω
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20μg
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XY5673-100μg
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Recombinant
Human IFN-ω
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100μg
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XY5673-1mg
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Recombinant
Human IFN-ω
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。