Recombinant Human LR3 IGF-1, Receptor Grade
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产品名称: Recombinant Human LR3 IGF-1, Receptor Grade
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human LR3 IGF-1, Receptor Grade由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human LR3 IGF-1, Receptor Grade所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human LR3 IGF-1, Receptor Grade
的详细介绍
Recombinant Human LR3 IGF-1, Receptor Grade
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产品编号
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产品名称
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产品包装
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产品价格
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XY547-10mg
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Recombinant
Human LR3 IGF-1, Receptor Grade
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10mg
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5393.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3479
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P05019
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E. coli
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83aa
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9.1kDa
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－
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About this
Protein
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Name
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Recombinant
Human LR3 IGF-1, Receptor Grade (Recombinant Human LR3 Insulin-like Growth
Factor-1; rHuLR3 IGF-1, Receptor Grade)；重组人LR3胰岛素样生长因子1
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Synonyms
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IGF1; IGF-1;
Somatomedin A; Somatomedin C; IBP1; IGF1A; IGFI; IGF-I; IGF-IA; IGF-IB;
insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C);
insulin-like growth factor I; insulin-like growth factor IA; insulin-like
growth factor IB; Mechano growth factor; MGF; somatomedin-C; Somatomedin-C
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Purity
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>98% by
SDS-PAGE analyses. >95% by RP-HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by the
stimulation of protein synthesis using rat L6 myoblasts is less than 10ng/ml,
corresponding to a specific activity of >1.0×105IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.0.
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Endotoxin
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Less than
50EU/mg of rHuLR3 IGF-1 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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IGF-1 belonged
to the insulin gene family, is a mitogenic polypeptide growth factor that
stimulate the proliferation and survival of various cell types including
muscle, bone, and cartilage tissue in vitro. It is produced primarily by the
liver as an endocrine hormone as well as in target tissues in a
paracrine/autocrine fashion. The production of IGF-1 is stimulated by growth
hormone (GH) and can be retarded by undernutrition, growth hormone
insensitivity, lack of growth hormone receptors, or failures of the
downstream signaling pathway post GH receptor including SHP2 and STAT5B. The
LR3 IGF-1 is a long-term analog of human IGF-1, specifically designed and
manufactured for mammalian cell culture to support large-scale manufacturing
of recombinant biopharmaceuticals.
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Amino Acid
Sequence
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MFPAMPLSSL FVNGPRTLCG AELVDALQFV
CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
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包装清单:
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产品编号
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产品名称
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包装
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XY547-100μg
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Recombinant
Human LR3 IGF-1, Receptor Grade
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100μg
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XY547-1mg
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Recombinant
Human LR3 IGF-1, Receptor Grade
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1mg
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XY547-10mg
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Recombinant
Human LR3 IGF-1, Receptor Grade
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10mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。