Recombinant Human 4-1BB Receptor/TNFRSF9
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产品名称: Recombinant Human 4-1BB Receptor/TNFRSF9
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human 4-1BB Receptor/TNFRSF9由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human 4-1BB Receptor/TNFRSF9所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human 4-1BB Receptor/TNFRSF9
的详细介绍
Recombinant Human 4-1BB Receptor/TNFRSF9
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产品编号
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产品名称
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产品包装
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产品价格
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XY399-1mg
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Recombinant
Human 4-1BB Receptor/TNFRSF9
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3604
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Q07011
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E. coli
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166aa
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17.7kDa
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－
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About this
Antibody
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Name
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Recombinant
Human 4-1BB Receptor/TNFRSF9 (Recombinant Human 4-1BB Receptor; rHu4-1BB
Receptor)；重组人4-1BB受体/TNFRSF9
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Synonyms
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CD137; ILA;
TNFRSF9; 4-1BB; 4-1BB ligand receptor; CD137 antigen; CD137MGC2172; CDw137;
FLJ43501; ILAhomolog of mouse 4-1BB; induced by lymphocyte activation (ILA);
interleukin-activated receptor, homolog of mouse Ly63; receptor protein
4-1BB; T cell antigen ILA; T-cell antigen 4-1BB homolog; T-cell antigen ILA;
tumor necrosis factor receptor superfamily member 9; tumor necrosis factor
receptor superfamily, member 9
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The biological activity is
determined by its inhibitory effect of IL-8 production using human peripheral
blood mononuclear cells. About 90% of inibition was seen using a
concentration of 1μg for both 4-1BB Ligand and 4-1BB Receptor.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 10mM PB, pH8.0,
150mM NaCl.
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Endotoxin
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Less than 1EU/μg of rHu4-1BB Receptor as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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4-1BB
receptor, also named TNFRSF9 is a member of the TNF superfamily of receptors.
It is mainly expressed on the surface of a variety of T cells, but also found
in B cells, monocytes, and various transformed cell lines. 4-1BB receptor
binds to 4-1BBL, and they co-stimulate activity for activated T cells.
Signaling by 4-1BB Receptor has been implicated in the antigen-presentation
process and generation of cytotoxic T cells. Crosslinking of 4-1BB Receptor
enhances T cell proliferation, IL-2 secretion survival and cytolytic
activity. Further, it can enhance immune activity to eliminate tumors in
mice.
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Amino Acid
Sequence
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ERTRSLQDPC SNCPAGTFCD NNRNQICSPC
PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK
DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS
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包装清单:
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产品编号
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产品名称
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包装
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XY399-5μg
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Recombinant
Human 4-1BB Receptor/TNFRSF9
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5μg
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XY399-20μg
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Recombinant
Human 4-1BB Receptor/TNFRSF9
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20μg
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XY399-100μg
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Recombinant
Human 4-1BB Receptor/TNFRSF9
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100μg
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XY399-1mg
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Recombinant
Human 4-1BB Receptor/TNFRSF9
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。