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产品名称: Recombinant Human IL-5
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human IL-5由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human IL-5所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human IL-5
的详细介绍
Recombinant Human IL-5
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产品编号
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产品名称
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产品包装
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产品价格
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XY133-1mg
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Recombinant
Human IL-5
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1mg
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22133.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3567
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P05113
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E. coli
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116aa
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26.5kDa
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－
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About this
protein
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Name
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Recombinant
Human IL-5 (Recombinant Human Interleukin-5; rHuIL-5)；重组人白细胞介素5
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Synonyms
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BCDF mu;
BCGFII; EDF; Eo-CSF; TRF; B-cell differentiation factor I; EDF; Eosinophil
differentiation factor; IL-5T-cell replacing factor; interleukin 5
(colony-stimulating factor, eosinophil); interleukin-5; TRFB cell
differentiation factor I
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Purity
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>98% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferationassay using human TF-1 cells is less than 0.1ng/ml,
corresponding to a specific activity of >1.0×107IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 20mM PB, pH7.5, 3%
trehalose, 0.1% Tween-80.
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Endotoxin
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Less than 1EU/μg of rHuIL-5 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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The IL-5 gene
is located on chromosome 5 in humans, in close proximity to the genes
encoding IL-3, IL-4, and granulocytemacrophage colony-stimulating factor
(GM-CSF), which are often co-expressed in TH2 cells. Through binding to the
IL-5 receptor, IL-5 stimulates B cell growth and increases immunroglobulin
secretion. It is also a key mediator in eosinophil activation. Interleukin-5
has long been associated with the cause of several allergic diseases
including allergic rhinitis and asthma. IL-5 is a 115-amino acid (in human,
133 in the mouse) -long TH2 cytokine that is part of the hematopoietic
family. Unlike other members of this cytokine family (namely IL-3 and
GM-CSF), this glycoprotein in its active form is a homodimer.
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Amino Acid
Sequence
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MIPTEIPTSA LVKETLALLS THRTLLIANE
TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY
LQEFLGVMNT EWIIES
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包装清单:
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产品编号
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产品名称
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包装
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XY133-2μg
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Recombinant
Human IL-5
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2μg
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XY133-10μg
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Recombinant
Human IL-5
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10μg
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XY133-100μg
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Recombinant
Human IL-5
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100μg
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XY133-1mg
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Recombinant
Human IL-5
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。