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产品名称: Recombinant Human IL-2
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human IL-2由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human IL-2所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human IL-2
的详细介绍
Recombinant Human IL-2
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产品编号
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产品名称
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产品包装
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产品价格
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XY115-1mg
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Recombinant
Human IL-2
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1mg
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4115.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3558
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P60568
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E. coli
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133aa
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15.4kDa
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－
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About this
protein
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Name
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Recombinant
Human IL-2 (Recombinant Human Interleukin-2; rHuIL-2)；重组人白细胞介素2
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Synonyms
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aldesleukin;
Aldesleukin; IL-2lymphokine; interleukin 2; interleukin-2; involved in
regulation of T-cell clonal expansion; T cell growth factor; T-cell growth
factor; TCGF
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using murine CTLL-2 cells is less than 0.1ng/ml,
corresponding to a specific activity of >1.0×107IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH5.0.
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Endotoxin
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Less than 1EU/μg of rHuIL-2
as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled H2O to a
concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into
working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered
solutions. Do not reconstitute in cell culture media directly.
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Category
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Cytokine
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Background
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IL-2 is a
powerful immunoregulatory lymphokine produced by T-cells in response to
antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells and eosinophils. IL-2/IL-2R
signaling is required for T-cell proliferation and other fundamental
functions which are essential for the immune response. The receptor for IL-2
consists of three subunits (55kDa IL-2Rα, 75kDa IL-2Rβ, and 64kDa common gamma chain γc/IL-2Rγ) that are present on the cell surface in varying preformed
complexes. Mature human IL-2 shares 56% and 66% amino acid sequence identity
with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit
cross-species activity.
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Amino Acid
Sequence
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APTSSSTKKT QLQLEHLLLD LQMILNGINN
YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE
TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT
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包装清单:
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产品编号
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产品名称
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包装
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XY115-10μg
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Recombinant
Human IL-2
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10μg
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XY115-50μg
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Recombinant
Human IL-2
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50μg
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XY115-100μg
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Recombinant
Human IL-2
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100μg
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XY115-1mg
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Recombinant
Human IL-2
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。