亮氨酸氨基肽酶3抗体
规格：1mg/1ml
英文名： LAP3
别名： Cytosol aminopeptidase; LAP 3; LAP; LAPEP; Leucine aminopeptidase 3; Leucyl aminopeptidase; PEPS; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase; AMPL_HUMAN.
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LAP3
交叉反应：Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位：细胞浆
亮氨酸氨基肽酶3抗体产品介绍：background: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome,亮氨酸氨基肽酶3抗体 methylmalonic acidemia and polycystic kidney disease. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Subunit: Homohexamer. Subcellular Location: Cytoplasmic Similarity: Belongs to the peptidase M17 family. Gene ID: 51056 Database links: Entrez Gene: 51056 Human Entrez Gene:亮氨酸氨基肽酶3抗体 66988 Mouse Entrez Gene: 289668 Rat Omim: 170250 Human SwissProt: P28838 Human SwissProt: Q9CPY7 Mouse SwissProt: Q68FS4 Rat Unigene: 570791 Human Unigene: 286830 Mouse Unigene: 99790 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
亮氨酸氨基肽酶3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liqui