心肌锚蛋白重复结构域1抗体
规格：1mg/1ml
英文名： ANKRD1
别名： ALRP; ANKR1_HUMAN; ANKRD 1; ANKRD1; Ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain containing protein 1; Ankyrin repeat domain-containing protein 1; C 193; C193; Cardiac ankyrin repea
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ANKRD1
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞核
心肌锚蛋白重复结构域1抗体产品介绍：background: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Function: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Subunit: Interacts with YBX1 (By similarity). Interacts with TTN/titin. Subcellular Location: Nucleus. Tissue Specificity: Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. DISEASE: Defects in ANKRD1 may be a cause of total anomalous pulmonary venous心肌锚蛋白重复结构域1抗体 return (TAPVR) . TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximately 1 out of 15'000 live births. Similarity: Contains 5 ANK repeats. Gene ID: 27063 Database links: Entrez Gene: 27063 Human Entrez Gene: 107765 Mouse Entrez Gene: 27064 Rat Omim: 609599 Human SwissProt: Q15327 Human SwissProt: Q9CR42 心肌锚蛋白重复结构域1抗体Mouse SwissProt: Q8R560 Rat Unigene: 448589 Human Unigene: 10279 Mouse Unigene: 3789 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
心肌锚蛋白重复结构域1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 **学 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid