G蛋白α抑制蛋白1抗体
规格：1mg/1ml
英文名： GNAI2/G protein alpha inhibitor 1
别名： G alpha i-1; G Protein alpha Inhibitor 1; Adenylate cyclase inhibiting G alpha; Gi; Gi1 protein alpha subunit; Gi2 protein alpha subunit; GIP; GNAI1; GNAI2; GNAI2B; Guanine nucleotide binding protein
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human G Protei
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
G蛋白α抑制蛋白1抗体产品介绍：background: The G protein family of signal transducers includes 5 heterotrimers, which are most clearly distinguished by their different alpha chains; they have virtually identical beta chains and similar gamma chains. G protein alpha inhibitor chains 1 and 2 are subunits of the G(i) G protein, whose role is in inhibiting adenylate cyclase activity in response to bound GTP. Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool. Subunit: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1G蛋白α抑制蛋白1抗体. Interacts with RGS12 and RGS14. Interacts with UNC5B. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cell membrane. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. Similarity: Belongs to the G-alpha family. G(i/o/t/z) subfamily. Gene ID: 2771 Database links: Entrez Gene: 2771 Human Entrez Gene: 14678 Mouse Entrez Gene: 81664 Rat Omim: 139360 Human SwissProt: P04899 Human SwissProt: P08752 Mouse SwissProt: P04897 Rat Unigene: 77269 Human Unigene: G蛋白α抑制蛋白1抗体196464 Mouse Unigene: 3036 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Gα i-1/2/3
G蛋白α抑制蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid