胞浆区相关蛋白GIPC2抗体
规格:1mg/1ml
英文名: GIPC-2
别名: GIPC 2; GIPC-2 GIPC PDZ domain containing family, member 2; GIPC2; GIPC2_HUMAN; Likely ortholog of mouse semaF cytoplasmic domain associated protein 2; PDZ domain protein GIPC2; PDZ domain-containing
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GIPC2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
胞浆区相关蛋白GIPC2抗体产品介绍:background: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in ***** liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of胞浆区相关蛋白GIPC2抗体 the human genome. Subunit: Probably interacts with SEMA5A (By similarity). . Subcellular Location: Cytoplasm. Tissue Specificity: Expressed at highest levels in ascending colon and at moderate levels in ***** kidney. Expressed at low levels in ***** pancreas and at very low levels in ***** liver. Expression is down-regulated in several primary tumors, such as kidney, colon and rectal tumors. Similarity: Contains 1 PDZ (DHR) domain. Database links: UniProtKB/Swiss-Prot: Q8TF65.1 Important Note: This product as supplied is intended for research use only,胞浆区相关蛋白GIPC2抗体 not for use in human, therapeutic or diagnostic applications.
胞浆区相关蛋白GIPC2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid