硒蛋白Z抗体
规格：1mg/1ml
英文名： SELZ
别名： mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta;
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SELZ
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse,
细胞定位：
硒蛋白Z抗体产品介绍：background: This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013] Function: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling. Subunit: Homodimer. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed 硒蛋白Z抗体in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. Gene ID: 10587 Database links: Entrez Gene: 10587 Human Entrez Gene: 26462 Mouse Entrez Gene: 50551 Rat Omim: 606448 Human SwissProt: Q9NNW7 Human SwissProt: 硒蛋白Z抗体Q9JLT4 Mouse SwissProt: Q9Z0J5 Rat Unigene: 443430 Human Unigene: 390906 Mouse Unigene: 6300 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硒蛋白Z抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid