组蛋白去甲基转移酶JMJD7抗体
规格：1mg/1ml
英文名： JMJD7
别名： JmjC domain-containing protein 7; JMJD7; JMJD7_HUMAN; Jumonji domain containing 7; Jumonji domain-containing protein 7.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human JMJD7
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：
组蛋白去甲基转移酶JMJD7抗体产品介绍：background: A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin. This regulation has profound effects on the expression of genes and is part of an epigenetic memory network that determines cell fate. JMJD7 (Jumonji domain-containing protein 7) is a member of a family of JMJC domain-containing histone demethylases that are directly involved in removing methyl residues from distinct and unique lysine residues. These actions are组蛋白去甲基转移酶JMJD7抗体 implicated in gene expression and the regulation of cell senescence. JMJC domain-containing histone demethylases are also likely involved in development via their ability to regulate gene expression. JMJD7 contains one JMJC domain and was originally thought to be an alternatively spliced isoform of PLA2G4B. Similarity: Contains 1 JmjC domain. Database links: Entrez Gene: 100137047 Human Entrez Gene: 组蛋白去甲基转移酶JMJD7抗体433466 Mouse Entrez Gene: 100137086 Rat SwissProt: P0C870 Human SwissProt: P0C872 Mouse Unigene: 198161 Human Unigene: 482417 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组蛋白去甲基转移酶JMJD7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid