富含亮氨酸重复序列LRP15抗体
规格：1mg/1ml
英文名： LRP15
别名： LRP 15; LRP-15; Leucine rich repeat containing 3B; Leucine-rich repeat protein LRP15; Leucine-rich repeat-containing protein 3B; LRC3B_HUMAN; LRRC3B; MGC102927.
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LRP15
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit,
细胞定位：细胞膜
富含亮氨酸重复序列LRP15抗体产品介绍：background: Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene富含亮氨酸重复序列LRP15抗体 encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Similarity: Belongs to the LRRC3 family. Contains 3 LRR (leucine-rich) repeats. Contains 1 LRRCT 富含亮氨酸重复序列LRP15抗体domain. Contains 1 LRRNT domain. Database links: Entrez Gene: 420657 Chicken Entrez Gene: 116135 Human Entrez Gene: 218763 Mouse SwissProt: Q96PB8 Human SwissProt: Q8VCH9 Mouse Unigene: 517868 Human Unigene: 138039 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含亮氨酸重复序列LRP15抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid