ASH1蛋白抗体
规格：1mg/1ml
英文名： ASH1L
别名： Absent small and homeotic disks protein 1 homolog; Absent Small or Homeotic Like; ASH 1; ASH 1L; ash1 (absent small or homeotic 1); Ash1 (absent small or homeotic) like; Absent small and homeotic disk
分子量： 327kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ASH1L
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
细胞定位：细胞核 细胞膜
ASH1蛋白抗体产品介绍：background: ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation. Function: Histone methyltransferase. Probably methylates 'Lys-4' of histone H3,ASH1蛋白抗体 a specific tag for epigenetic transcriptional activation. Subcellular Location: Nucleus. Cell junction, tight junction. Chromosome (Probable). Note=The relevance of tight junction localization is however unclear. Tissue Specificity: Widely expressed, with highest level in brain, heart and kidney. Similarity: Belongs to the histone-lysine methyltransferase family. SET2 subfamily. Contains 3 A.T hook DNA-binding domains. ASH1蛋白抗体Contains 1 AWS domain. Contains 1 BAH domain. Contains 1 bromo domain. Contains 1 PHD-type zinc finger. Contains 1 post-SET domain. Contains 1 SET domain. Database links: Entrez Gene: 55870 Human Omim: 607999 Human SwissProt: Q9NR48 Human Unigene: 491060 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ASH1蛋白抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid