20号染色体开放阅读框103抗体
规格：1mg/1ml
英文名： C20orf103
别名： Chromosome 20 open reading frame 103; LAMP5_HUMAN.
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C20orf10
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞浆 细胞膜
20号染色体开放阅读框103抗体产品介绍：background: Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf103 gene product has been provisionally designated C20orf103 pending further characterization. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle (By similarity). Cell projection, dendrite (By similarity). Cell projection, growth cone20号染色体开放阅读框103抗体 membrane; Single-pass type I membrane protein (By similarity). Early endosome membrane; Single-pass type I membrane protein (By similarity). Recycling endosome (By similarity). Note=Localized mostly in cytoplasmic vesicles of neuronal cell body. Recycles from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (By similarity). Colocalizes with UNC93B1 in large endosomal intracellular vesicles. Accumulates in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) before its disappearance upon activation by CpG dinucleotides. Associates with cortical membranes. Tissue Specificity: Expressed in plasmocytoid dendritic cells. Expressed in suprabasal skin20号染色体开放阅读框103抗体 keratinocytes and squamous cells (at protein level). Expressed in the brain and weakly in spleen and skin. Expressed in plasmocytoid dendritic cells. Post-translational modifications: Glycosylated. Similarity: Belongs to the LAMP family. Database links: Entrez Gene: 24141 Human Entrez Gene: 76161 Mouse Entrez Gene: 36220 Rat SwissProt: A4FV27 Cow SwissProt: Q9UJQ1 Human SwissProt: Q9D387 Mouse SwissProt: Q5PPI4 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
20号染色体开放阅读框103抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid