颗粒酶K抗体
规格:1mg/1ml
英文名: Granzyme K
别名: Fragmentin 3; Fragmentin-3; Fragmentin3; GRAK_HUMAN; Granzyme 3; Granzyme K; Granzyme K precursor; Granzyme-3; Granzyme3; GranzymeK; GZMK; NK TRYP 2; NK TRYP2; NK tryptase 2; NK-TRYP-2; NK-tryptase-2;
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Granzyme
交叉反应:Human, Mouse, Rat, Horse,
颗粒酶K抗体细胞定位:细胞浆 分泌型蛋白
产品介绍:background: This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation 颗粒酶K抗体present in other granzymes. [provided by RefSeq, Jul 2008]. Subcellular Location: Secreted. Cytoplasmic granule. Tissue Specificity: Expressed in lung, spleen, thymus and peripheral blood leukocytes. Similarity: Belongs to the peptidase S1 family. Granzyme subfamily. Contains 1 peptidase S1 domain. Gene ID: 3003 Database links: Entrez Gene: 3003 Human Entrez Gene: 14945 Mouse Entrez Gene: 29165 Rat颗粒酶K抗体 Omim: 600784 Human SwissProt: P49863 Human SwissProt: O35205 Mouse SwissProt: P49864 Rat Unigene: 277937 Human Unigene: 56993 Mouse Unigene: 11190 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
颗粒酶K抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 细胞凋亡 转录调节因子 细胞外基质
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid