剪接因子，精氨酸/丝氨酸丰富19
规格：1mg/1ml
英文名： SFR19
别名： SCAF; Splicing factor, arginine/serine-rich 19; SR-related and CTD-associated factor 1; SR-related-CTD-associated factor; Serine arginine-rich pre-mRNA splicing factor SR-A1; SR-A1; SFR19_HUMAN.
分子量： 139kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SFR19/SC
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞核
剪接因子，精氨酸/丝氨酸丰富19产品介绍：background: SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers. Function: May function in pre-mRNA splicing (By similarity). Subunit: Interacts with POLR2A. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous剪接因子，精氨酸/丝氨酸丰富19. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa. 剪接因子，精氨酸/丝氨酸丰富19Similarity: Belongs to the splicing factor SR family. Database links: UniProtKB/Swiss-Prot: Q9H7N4.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产剪接因子，精氨酸/丝氨酸丰富19品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 染色质和核信号 信号转导 肿瘤细胞生物标志物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid