钠通道蛋白8α抗体
规格：1mg/1ml
英文名： SCN8A/Nav1.6
别名： CerIII; hNa6/Scn8a voltage gated sodium channel; MED; Motor endplate disease; NaCh 6; NaCh6; Nav 1.6; Nbna1; PN 4; PN4; Scn8a; SCN8A_HUMAN; Sodium channel protein type 8 alpha subunit; Sodium channel
分子量： 220kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SCN8A/Na
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞浆
钠通道蛋白8α抗体产品介绍：background: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation. Function: Implicated in the suppression of cell death. Interacts 钠通道蛋白8α抗体with the BCL-2 and adenovirus E1B 19 kDa proteins. Subcellular Location: Cytoplasm. Cytoplasm, perinuclear region. Similarity: Contains 1 CRAL-TRIO domain. Database links: Entrez Gene: 537277 Cow Entrez Gene: 477604 Dog Entrez Gene: 6334 Human Entrez Gene: 20273 Mouse Entrez Gene: 29710 Rat Omim: 600702 Human SwissProt: Q9UQD0 Human SwissProt: Q9WTU3 Mouse SwissProt: 钠通道蛋白8α抗体O88420 Rat Unigene: 710638 Human Unigene: 385012 Mouse Unigene: 91216 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钠通道蛋白8α抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid