G蛋白激活内向钾通道3抗体
规格:1mg/1ml
英文名: GIRK3
别名: G protein activated inward rectifier potassium channel 3; G protein coupled inward rectifier potassium channel; G protein-activated inward rectifier potassium channel 3; GIRK-3; GIRK3; Inward rectifie
分子量: 43kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GIRK3/KC
交叉反应:Human, Mouse, Rat, Pig, Cow,
细胞定位:细胞膜
G蛋白激活内向钾通道3抗体产品介绍:background: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Function: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium toG蛋白激活内向钾通道3抗体 flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Subunit: Associates with GIRK1 to form a G-protein-activated heteromultimer pore-forming unit Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the inward rectifier-type potassium channel G蛋白激活内向钾通道3抗体(TC 1.A.2.1) family. KCNJ9 subfamily. Database links: UniProtKB/Swiss-Prot: Q92806.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白激活内向钾通道3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 神经生物学 信号转导 通道蛋白 G蛋白偶联受体 细胞表面分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid