骨形态发生蛋白15抗体
规格：1mg/1ml
英文名： BMP15
别名： BMP 15; BMP-15; BMP15; BMP15_HUMAN; Bone morphogenetic protein 15; GDF 9B; GDF-9B; GDF9B; Growth/differentiation factor 9B; ODG2; POF4.
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BMP15
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：分泌型蛋白
骨形态发生蛋白15抗体产品介绍：background: The BMP15 protein is a member of the bone morphogenetic protein family which is part of the transforming growth factor beta superfamily. The transforming growth factor beta superfamily includes large families of growth and differentiation factors. It is thought that BMP15 may be involved in oocyte maturation and follicular development as a homodimer, or by forming heterodimers with a related protein, Gdf9. Function: May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. Subunit: Homodimer. But, in contrast to other members of this family, cannot be disulfide-linked. Subcellular Location: Secreted. DISEASE: Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2) 骨形态发生蛋白15抗体[MIM:300510]; also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea. Defects in BMP15 are the cause of premature ovarian failure type 4 (POF4) [MIM:300510]. An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low骨形态发生蛋白15抗体 estradiol. Similarity: Belongs to the TGF-beta family. Database links: UniProtKB/Swiss-Prot: O95972.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骨形态发生蛋白15抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 发育生物学 染色质和核信号 信号转导 干细胞 生长因子和** 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid