癌症亮氨酸拉链下调因子1抗体
规格：1mg/1ml
英文名： LDOC1
别名： BCUR1; Breast cancer up regulated 1; Breast cancer upregulated 1; Gm366; Leucine zipper down regulated in cancer 1; Leucine zipper protein down regulated in cancer cells; Leucine zipper protein down r
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LDOC1
交叉反应：Human, Dog, Pig, Horse, Rabbit,
癌症亮氨酸拉链下调因子1抗体细胞定位：细胞核
产品介绍：background: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]. Function: May have an important role in the development and/or progression of some cancers. Subcellular Location: Nucleus. 癌症亮氨酸拉链下调因子1抗体Tissue Specificity: Ubiquitously expressed with high levels in brain and thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined. Similarity: Belongs to the 癌症亮氨酸拉链下调因子1抗体LDOC1 family. Gene ID: 23641 Database links: Entrez Gene: 23641 Human Omim: 300402 Human SwissProt: O95751 Human Unigene: 45231 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
癌症亮氨酸拉链下调因子1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 染色质和核信号 信号转导 转录调节因子 肿瘤细胞生物标志物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid