丝氨酸/苏氨酸蛋白激酶KIST抗体
规格：1mg/1ml
英文名： KIST
别名： kinase interacting with leukemia-associated gene (stathmin); Kinase interacting with stathmin; KIS; KIS protein kinase; KIST; Serine threonine protein kinase Kist; Serine/threonine-protein kinase Kist
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIST/UHM
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：
产丝氨酸/苏氨酸蛋白激酶KIST抗体品介绍：background: The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the ***** nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]. Function: Upon serum stimulation, phosphorylates丝氨酸/苏氨酸蛋白激酶KIST抗体 CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). Subunit: Interacts with stathmin and CDKN1B/p27Kip1 (By similarity). Subcellular Location: Nucleus. Note=Mostly nuclear (By similarity). Tissue Specificity: Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. 丝氨酸/苏氨酸蛋白激酶KIST抗体Contains 1 RRM (RNA recognition motif) domain. Database links: UniProtKB/Swiss-Prot: Q8TAS1.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产丝氨酸/苏氨酸蛋白激酶KIST抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 细胞周期蛋白 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid